I often drill and tap wood, MDF, and plywood for holding bolts, screws, and threaded inserts.

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I often drill and tap wood, MDF, and plywood for holding bolts, screws, and threaded inserts. One example: zero-clearance inserts with leveling setscrews. But I had a problem with the fasteners vibrating, enlarging the tapped holes, and moving.

To prevent that from happening, put a tiny drop of thin-bodied cyanoacrylate (instant) glue into each hole and spritz it with accelerator. Then make another pass with the tap to clean up the now-hardened threads. Add a bit of thread lock to the fastener and know that it won't again move on its own.
—Floyd Calderwood, Belfast, Maine